So much to my surprise, I found that not only did I feel stronger medication effects this week, but the side effects also returned. I was not expecting that with an increase of only 0.02mg! So I have decided that I don't plan on increasing this week and I'll stay at the 0.44mg until I'm not feeling those random bursts of nausea.
I wish they would run a study with a slower progression of doses. I am starting to believe that many of the side effects people experience are coming simply from the rapid increase in dose and our bodies may need more time to get used to it. It would be interesting to see if weight loss would decrease much because I bet quality of life would go way up. That being said, I've been taking the slow progression and I'm averaging a solid 1.78lbs per week, which is towards the high end of healthy weight loss. If I could have lost it a little faster but been nauseous all the time? Thanks, I'm good the way I'm doing things now.
Even if they can't design a study that says move up in a way that works for you, they could try different things like doubling the time interval from 4 weeks to 8 weeks, or halving the amount of the increase so you move up more slowly, or both. I think it would be interesting to see the results of this and if it has any measurable effects on both side effects, blood sugar control, and weight loss.
The other reason I wonder if a slower progression is better is that once you reach the high doses, where do you go from there once you develop a tolerance? You can't keep increasing if you've already reached the maximum. It feels like going more slowly would allow more space for increases when we stall. I've been lucky enough not to hit a plateau yet (which is defined as three or more weeks of zero weight change while still maintaining a calorie deficit- if you aren't doing that, it's not a plateau), but it's good to know that I will have space to increase if necessary.
I'm not a doctor so please don't take anything I say as medical advice. It's possible I'm missing something obvious that I don't even have the training to understand that I'm misunderstanding. I can only share my thoughts on my own experience with Ozempic.
OZ Week 3 gain: 2.0lbs
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